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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Migraine-associated seizures with recurrent and reversible magnetic resonance imaging abnormalities
Ignacio Mateo1, Nerea Foncea, Iñigo Vicente
1Neurology Service, Galdakao Hospital, Vizcaya, Spain.
Abstract:
Migraine and epilepsy are highly comorbid, but the nature of their association remains unclear. Exceptionally, reversible brain magnetic resonance imaging (MRI) abnormalities following migraine and seizures have been reported. There are no descriptions, however, of patients with recurrent brain MRI changes. We report a patient with repeated episodes of migraine-with-aura-associated seizures (migralepsy) and recurrent and reversible brain MRI abnormalities. Location of the abnormalities was always consistent with the neurologic deficits. The possibility that transient brain MRI abnormalities in a patient with migraine with aura followed by seizures may be due to migralepsy should be borne in mind to avoid misdiagnosis and potentially aggressive procedures.
Insights
Migraine and epilepsy share a strong link. This case study highlights recurrent, reversible brain MRI changes in a patient experiencing migraine with aura and seizures, a phenomenon termed migralepsy.
Area of Science:
- Neurology
- Neuroimaging
Background:
- Migraine and epilepsy frequently co-occur, yet the underlying mechanisms remain poorly understood.
- Reversible brain MRI abnormalities have been anecdotally linked to migraine and seizures.
Observation:
- This report details a unique patient experiencing recurrent episodes of migraine with aura-associated seizures (migralepsy).
- The patient exhibited recurrent and reversible brain magnetic resonance imaging (MRI) abnormalities that correlated with neurological deficits.
Findings:
- This case demonstrates the first description of recurrent, reversible brain MRI changes in a patient with migralepsy.
- The location of MRI abnormalities consistently matched the observed neurological symptoms.
Implications:
- Recognizing migralepsy as a cause of transient brain MRI changes is crucial for accurate diagnosis.
- Awareness of these findings can help prevent misdiagnosis and unnecessary, aggressive medical interventions.
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