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Risk factors for surgical site infections after pediatric cardiovascular surgery
Amanda L Allpress1, Geoffrey L Rosenthal, Kathy M Goodrich
1Children's Hospital and Regional Medical Center, University of Washington, Seattle, WA, USA.
Insights
Infants under one month and longer surgical times increase the risk of surgical site infections (SSI) after pediatric cardiovascular (CV) surgery. Identifying these risk factors is crucial for preventing infections in young patients.
Area of Science:
- Pediatric cardiovascular surgery
- Infectious disease epidemiology
- Healthcare-associated infections
Background:
- Surgical site infections (SSI) are a concern following cardiovascular (CV) surgery.
- Risk factors for SSI in adult CV surgery patients are known, but less so in pediatric populations.
- This study focuses on identifying SSI risk factors in children undergoing CV surgery.
Purpose of the Study:
- To identify independent risk factors for hospitalized surgical site infections (SSI) in children undergoing cardiovascular (CV) surgery.
- To provide data for targeted prevention strategies in pediatric CV surgery.
- To enhance patient safety in pediatric cardiac procedures.
Main Methods:
- A case-control study design was employed.
- National Nosocomial Infections Surveillance System criteria were used for SSI identification.
- Multivariable logistic regression analysis was performed to determine risk factors.
Main Results:
- The incidence of SSI was 2.3 per 100 CV surgeries in children.
- Infants younger than one month had a significantly higher risk (OR, 14).
- Longer duration of surgery was also independently associated with SSI (OR, 1.4).
Conclusions:
- Age less than one month is a critical risk factor for SSI after pediatric CV surgery.
- Prolonged surgical duration is independently associated with an increased risk of SSI in this population.
- These findings highlight the need for focused preventive measures in high-risk pediatric patients.
Background:
Although risk factors for surgical site infection (SSI) after cardiovascular (CV) surgery have been well-documented among adults, few studies have been conducted in children. We performed a case-control study to identify risk factors for hospitalized SSI in children undergoing CV surgery.
Methods:
National Nosocomial Infections Surveillance System criteria were used prospectively to identify cases of hospitalized SSI in patients who underwent CV surgery. Seventy-nine patients who underwent CV surgery without hospitalized SSI were randomly selected as controls. Cases were compared with controls to determine preoperative, intraoperative and postoperative risk factors for hospitalized SSI. Multivariable logistic regression was performed.
Results:
An SSI developed in 19 of the 826 patients who underwent CV surgery (2.3 cases per 100 surgeries) during the study period. Infection was limited to soft tissue in 12, whereas deeper infection occurred in 7. Causative agents included Staphylococcus aureus (11), coagulase-negative Staphylococcus (5) and Escherichia coli (2). One patient did not have a pathogen isolated. In a multivariable analysis, duration of surgery (odds ratio, 1.4; 95% confidence interval, 1.2 to 1.8) and age <1 month (odds ratio, 14; 95% confidence interval, 3.3 to 58.4) were independently associated with SSI.
Conclusions:
Age <1 month and longer duration of surgery were independently associated with hospitalized SSI after CV surgery in children.
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