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Updated: Aug 25, 2026

Purification of a High Molecular Mass Protein in Streptococcus mutans
Published on: September 14, 2019
[Binding ability of fluoride-resistant strains of S. mutans and S. sobrinus in vitro]
1Department of Stomatology, Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011, China.
Objective:
To investigate the binding ability of S.mutans and S.sobrinus after their fluoride-resistant mutation.
Methods:
The binding amount and binding percentage of S.mutans, S.sobrinus and their F-resistant strains to saliva-coated hydroxyapatite(SHA)were measured and compared by(3)H-labeled binding assay.
Results:
The binding percentages of F-resistant and their parent strains had few difference(P>0.05) whereas the binding percentage of S.sobrinus was significantly lower than S.mutans (P<0.01).
Conclusion:
The data showed that the binding ability to SHA between F-resistant and F-sensitive S.mutans had no significant difference which indicated that the emerge of F-resistant strains could not reduce the cariogenicity of S.mutans and S.sobrinus.
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