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Updated: Aug 26, 2026

Purification of a High Molecular Mass Protein in Streptococcus mutans
Published on: September 14, 2019
[Base composition of DNA from fluoride resistant strains of streptococcus mutans and streptococcus sobrinus]
1School of Stomatology, Shanghai Second Medical University, Shanghai 200011, China.
Objectives:
To evaluate the genotype change of fluoride-resistant strains of S.mutans and S.sobrinus.
Methods:
High potential liquid chromatography was used to measure the base composition of DNA from F-resistant strains of S.mutans and S.sobrinus and their parent strains.
Results:
The data showed that the DNA G+C mol% of F-resistant and F-sensitive S.mutans were quite different, the difference was over 5%. The four F-resistant strains were 54.45, 44.86, 54.41, 55, 390, whereas the corresponding four parent strains were 35.38, 37.4, 43.35, 46.62, respectively.
Conclusion:
The genotypes of F-resistant strains of S.mutans and S.sobrinus have been changed and may comprise several gene mutations.
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