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Related Experiment Videos

Exophthalmos in obesity.

M H Smolders1, H S Graniewski-Wijnands, A E Meinders

  • 1Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands.

Ophthalmic Research
|March 16, 2004
PubMed
Summary

Obesity is linked to increased exophthalmos (protruding eyes) and larger eye muscles, though without causing vision problems. These findings suggest standard measurements for eye protrusion may need adjustment for obese individuals.

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Area of Science:

  • Ophthalmology
  • Endocrinology
  • Public Health

Background:

  • Obesity is a growing global health concern.
  • Ocular manifestations in obese individuals are not well-documented.
  • Exophthalmos, or protruding eyes, can be associated with various conditions.

Purpose of the Study:

  • To investigate the relationship between obesity and exophthalmos.
  • To compare ocular measurements in obese versus non-obese individuals.

Main Methods:

  • Compared 19 obese patients (BMI >/=30 kg/m(2)) with 45 non-obese controls (20-26 kg/m(2)).
  • Utilized Hertel's exophthalmometry, Goldmann applanation tonometry, and echography for medial rectus muscle measurement.

Main Results:

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  • Obese patients exhibited significantly higher Hertel exophthalmometry values (p < 0.05).
  • Medial rectus muscle diameter was enlarged in obese individuals (p < 0.05).
  • Bilateral exophthalmos occurred in 33% of obese subjects, without associated ocular morbidity.
  • Conclusions:

    • Standard exophthalmometry and orbital echography values may require adaptation for obese populations.
    • Observed eye signs in obese patients can mimic Graves' orbitopathy.
    • Obesity should be considered a potential cause in patients presenting with bilateral exophthalmos and signs suggestive of Graves' orbitopathy.