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Evaluation and selection of potential live kidney donors
Ehab W Wafa1, Ahmed F Donia, Bedeir Ali-El-Dein
1Urology and Nephrology Center, Mansoura, Egypt.
Purpose:
Renal transplantation is an optimal therapy for patients with end stage kidney disease. A thorough evaluation of potential donors is necessary to provide the best functional outcome for recipients and ensure no or minimal morbidity for donors.
Materials And Methods:
Between 1992 and 2001, 1661 ABO compatible potential living donors were evaluated clinically as well as by laboratory and imaging studies.
Results:
Of 1661 potential donors 814 (49%) were excluded. The reasons for elimination were general medical reasons in 34.4% of cases, nephrological disorders in 25.6%, urological diseases in 11.7% and immunological causes in 16.2%. Exclusion on an ethical basis accounted for 12.2% of cases.
Conclusions:
Although kidneys from living donors provide the best functional outcome, 50% of potential candidates must be excluded.