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Updated: Jul 18, 2026
06:02
Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
Transient partial amnesia complicating cardiac and peripheral arteriography with nonionic contrast medium.
Altan Yildiz1, Esin Yencilek, F Demir Apaydin
1Department of Radiology, Mersin Universitesi Tip Fakültesi Hastanesi Radyoloji Anabilim Dali, Ihsaniye Mahallesi 123, Cadde 4931, 33079 Sokak Mersin, Turkey. ayildiz@mersin.edu.tr
European Radiology
|March 17, 2004
Summary
Intraarterial contrast media during angiography can disrupt the blood-brain barrier, causing temporary neurological symptoms and imaging changes. These effects resolved within 24 hours in this reported case.
Area of Science:
- Radiology
- Neurology
- Vascular Imaging
Background:
- Contrast media administration during angiography carries potential risks.
- Understanding the blood-brain barrier's response to contrast agents is crucial for patient safety.
Observation:
- A case of blood-brain barrier disruption occurred during coronary and lower extremity angiography.
- This disruption was linked to the intraarterial injection of a nonionic, monomeric contrast medium.
- A total of 450 cc of contrast media was administered.
Findings:
- Computed tomography revealed contrast enhancement in the right occipital and frontoparietal cortical regions.
- Neurological symptoms fully resolved within 24 hours.
- Radiological findings normalized one day post-procedure.
Implications:
- This case highlights a potential complication of angiography with specific contrast agents.
- Further research into the mechanism of contrast-induced blood-brain barrier disruption is warranted.
- Clinical vigilance is necessary to identify and manage such adverse events.
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