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Non-fermenters in human infections.
Usha Arora1, Aruna Aggarwal, Saroj Sofat
1Department of Microbiology, Government Medical College, Amritsar. drrkarora@glide.net.in
Indian Journal of Pathology & Microbiology
|March 17, 2004
Summary
This study identified common non-fermenting gram-negative bacteria, with Pseudomonas aeruginosa being the most frequent isolate. Most isolates exhibited multidrug resistance, highlighting a significant challenge in antimicrobial therapy.
Area of Science:
- Microbiology
- Bacteriology
- Antimicrobial Resistance
Background:
- Non-fermenting Gram-negative bacteria (NFGNB) are significant opportunistic pathogens.
- Pseudomonas aeruginosa is a leading cause of healthcare-associated infections.
- Understanding the prevalence and antibiotic susceptibility of NFGNB is crucial for infection control.
Purpose of the Study:
- To identify the common NFGNB species in clinical samples.
- To determine the antibiotic resistance patterns of these isolates.
Main Methods:
- Isolation and identification of 1130 NFGNB from various samples.
- Antibiotic susceptibility testing using standard microbiological methods.
Main Results:
- Pseudomonas aeruginosa was the most prevalent isolate (72.83%).
- Other common isolates included Acinetobacter anitratus and Alcaligenes faecalis.
- A high prevalence of multidrug resistance was observed, with most isolates resistant to two or more antibiotics.
Conclusions:
- Pseudomonas aeruginosa is a dominant NFGNB in the studied samples.
- The widespread multidrug resistance among NFGNB poses a significant therapeutic challenge.
- Effective infection control strategies and development of new antimicrobial agents are urgently needed.