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Updated: Aug 7, 2026

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Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer
Published on: August 2, 2018
Identification and analysis of phosphopeptides
Michael J Chalmers1, Walter Kolch, Mark R Emmett
1Ion Cyclotron Resonance Program, National High Magnetic Field Laboratory, Tallahassee, FL 32310-3706, USA.
Abstract:
Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites.

