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Updated: Aug 18, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
[Extensive peripapillary myelinated nerve fibers, high ipsilateral myopia and refractory amblyopia]
M Laghmari1, N Boutimzine, A Karim
1Service d'Ophtalmologie A, Hôpital des Spécialités, Rabat, Maroc.
Introduction:
Extensive peripapillary myelinated nerve fibers can be associated with myopic anisometropia amblyopia. Despite aggressive occlusion of the good eye, visual results are often disappointing, probably because of structural anomalies of the macula, limiting visual potential.
Observation:
The authors report the case of a 5-year-old girl presenting extensive peripapillary myelinated nerve fibers associated with myopic anisometropia. Amblyopia did not respond to optical correction and continuous occlusion of the good eye for 9 weeks.
Discussion:
Certain authors report obtaining good results with aggressive treatment of amblyopia associated with extensive peripapillary myelinated nerve fibers and myopic anisometropia. However, the majority of the few series published in the literature report that amblyopia related to this pathology is particularly refractory to treatment, as confirmed by the case study presented herein.
Conclusion:
Despite a certain number of cases with a good prognosis reported in associated peripapillary myelinated nerve fibers and ipsilateral myopia, we believe that its visual prognosis remains reserved and that patients and/or their families should be provided with appropriate information.
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