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What is the daily practice of mechanical ventilation in pediatric intensive care units? A multicenter study
J A Farias1, F Frutos, A Esteban
1Unidad de Cuidados Intensivos Pediátricos, Hospital de Niños R Gutiérrez, B de Irigoyen 49, 1834 Temperley, Buenos Aires, Argentina. jufarias@intramed.net.ar
Insights
Mechanical ventilation (MV) is required by 35% of pediatric intensive care unit (PICU) patients, primarily for acute respiratory failure (ARF). Overall survival for these critically ill children receiving MV for over 12 hours is 85%.
Area of Science:
- Pediatric Critical Care Medicine
- Respiratory Medicine
- Clinical Research
Background:
- Mechanical ventilation (MV) is a cornerstone of critical care for infants and children.
- Understanding the daily practice and outcomes of MV in pediatric intensive care units (PICUs) is crucial for optimizing patient care.
Purpose of the Study:
- To describe the current practice patterns of mechanical ventilation (MV) in pediatric intensive care units (PICUs).
- To evaluate the outcomes associated with MV in a broad population of infants and children.
Main Methods:
- A prospective cohort study was conducted across 36 medical-surgical PICUs.
- Data were collected on all consecutive patients requiring MV for at least 12 hours over a 2-month period.
Main Results:
- Of 1893 admitted patients, 659 (35%) received MV, with a median duration of 4 days.
- Acute respiratory failure (ARF) was the primary indication for MV (72%), followed by altered mental status (14%).
- The overall PICU mortality rate was 15%, with higher mortality observed in patients with ARDS (50%) and altered mental status (24%).
Conclusions:
- Approximately one-third of PICU admissions necessitate ventilatory support.
- Acute respiratory failure is the most frequent indication for MV in pediatric patients.
- The survival rate for unselected infants and children receiving MV for over 12 hours was 85%.
Objective:
To describe the daily practice of mechanical ventilation (MV), and secondarily, its outcome in pediatric intensive care units (PICUs).
Design:
Prospective cohort of infants and children who received MV for at least 12 h.
Setting:
Thirty-six medical surgical PICUs.
Patients:
All consecutive patients admitted to the PICUs during 2-month period.
Measurements And Main Results:
Of the 1893 patients admitted, 659 (35%) received MV for a median time of 4 days (25th percentile, 75%: 2, 6). Median of age was 13 months (25th percentile, 75%: 5, 48). Common indications for MV were acute respiratory failure (ARF) in 72% of the patients, altered mental status in 14% of the patients, and ARF on chronic pulmonary disease in 10% of the patients. Median length of stay in the PICUs was 8 days (25th percentile, 75%: 5, 13). Overall mortality rate in the PICUs was 15% (confidence interval 95%: 13-18) for the entire population, 50% (95% CI: 25-74) in patients who received MV because of acute respiratory distress syndrome, 24% (95% CI: 16-35) in patients who received MV for altered mental status and 16% (95% CI: 9-29) in patients who received MV for ARF on chronic pulmonary disease.
Conclusion:
One in every 3 patients admitted to the PICUs requires ventilatory support. The ARF was the most common reason for MV, and survival of unselected infants and children receiving MV for more than 12 h was 85%.
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