Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endothelial cell integrity after phacoemulsification with 2 different handpieces.

Luis G Vargas1, Mike P Holzer, Kerry D Solomon

  • 1Magill Research Center for Vision Correction, Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.

Journal of Cataract and Refractive Surgery
|March 20, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Severity-Graded Repeatability of AS-OCT Including Epithelial and Stromal Metrics in Patients With Keratoconus Versus Healthy Individuals.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2026
Same author

An Update on Intraocular Lens Technology for Presbyopia Correction and Visual Outcomes.

Medical sciences (Basel, Switzerland)·2026
Same author

[Patient selection for unilateral cataract : Case report on a dysphotopsia-optimized, nondiffractive, presbyopia-correcting intraocular lens].

Die Ophthalmologie·2026
Same author

Estimating Range of Vision and Optical Function Related to Pupil Size in a Spiral Intraocular Lens.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2026
Same author

Visual function comparison of a non-diffractive extended depth-of-focus and an enhanced monofocal intraocular lens sharing the same platform.

Scientific reports·2026
Same author

Variation in resistance force during intraocular lenses injection by modern injectors and assessment of damage to the injector: a laboratory analysis.

Scientific reports·2026

A new oscillatory handpiece significantly reduced corneal endothelial cell loss during phacoemulsification (PE) compared to conventional methods. This finding suggests a gentler approach for cataract surgery, preserving vital eye cells.

Area of Science:

  • Ophthalmology
  • Cell Biology

Background:

  • Phacoemulsification (PE) is a common cataract surgery technique.
  • Corneal endothelial cell loss is a critical concern following PE.

Purpose of the Study:

  • To compare corneal endothelial cell loss after PE using a conventional handpiece versus a novel oscillatory handpiece.
  • To evaluate the safety and efficacy of the oscillatory handpiece in preserving corneal endothelium.

Main Methods:

  • Twenty human autopsy eyes were randomized for PE with either a conventional or oscillatory handpiece.
  • Key parameters included nucleus density, ophthalmic viscosurgical device (OVD) usage, and ultrasound (US) power.
  • Endothelial cell loss was assessed via vital staining and light microscopy.

Main Results:

Related Experiment Videos

  • Phacoemulsification time was shorter with the oscillatory handpiece (NeoSoniX).
  • Significantly lower corneal endothelial cell loss was observed with the oscillatory handpiece (31.3 cells/mm²) compared to the conventional handpiece (60.4 cells/mm²).
  • No significant differences in age, nucleus density, OVD used, or US power were noted between groups.

Conclusions:

  • The oscillatory handpiece resulted in less corneal endothelial cell loss during phacoemulsification.
  • This suggests the oscillatory handpiece may offer a gentler alternative for cataract surgery.
  • Further clinical trials are recommended to confirm these findings.