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Updated: Aug 25, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Detection of laser in situ keratomileusis in a postmortem eye using optical coherence tomography
Armin H Wolf1, Aljoscha S Neubauer, Siegfried G Priglinger
1Eye Clinic, Ludwig-Maximilians-Universität, Munich, Germany.
Abstract:
With more individuals having laser in situ keratomileusis (LASIK), eye banks are challenged to detect prior refractive surgery in donor tissue. We report the case of a donor who had LASIK 9 months before his death. Slitlamp biomicroscopy, corneal topography, and optical coherence tomography (OCT) were performed to evaluate the corneas. Few changes were detected under slitlamp examination and corneal topography. We demonstrate that OCT is capable of detecting LASIK-induced structural changes in the immediate postmortem evaluation and during the early and late period of organ culture. We recommend OCT screening of potential donor corneas before organ culture and between days 9 and 12 of organ culture.
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