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Delayed postanoxic encephalopathy: a case report and literature review
Christian M Custodio1, Jeffrey R Basford
1Department of Physical Medicine & Rehabilitation, Mayo Clinic and Foundation, Rochester, MN, USA.
Archives of Physical Medicine and Rehabilitation
|March 20, 2004
Summary
Delayed postanoxic encephalopathy (DPE) can cause sudden neurological decline after initial recovery from hypoxia. This case highlights DPE
Area of Science:
- Neurology
- Neuroscience
- Critical Care Medicine
Background:
- Delayed postanoxic encephalopathy (DPE) is a rare neurological condition following hypoxic or anoxic events.
- It is characterized by a delayed relapse of neurological deficits after apparent recovery.
Observation:
- A 51-year-old woman admitted for rehabilitation after respiratory arrest developed parkinsonian symptoms and severe pain.
- Her condition rapidly worsened, leading to immobility and inability to perform daily activities.
Findings:
- The patient was diagnosed with delayed postanoxic encephalopathy.
- She showed improvement with carbidopa/levodopa and modified physical/occupational therapy.
Implications:
- This case underscores the importance of considering DPE in patients with sudden neurological deterioration post-anoxia.
- Early recognition and intervention may improve outcomes in delayed postanoxic encephalopathy.