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The use of clopidogrel in patients with coronary artery disease

Erdal Cavuşoğlu1

  • 1Interventional Cardiology SUNY Downstate Medical Center, Brooklyn, New York 11203-2098, USA. ECavusoglu@aol.com

Anadolu Kardiyoloji Dergisi : AKD = the Anatolian Journal of Cardiology
|March 23, 2004
PubMed

Insights

Clopidogrel, an antiplatelet medication, is a key treatment for coronary artery disease by inhibiting platelet aggregation. This thienopyridine effectively manages arterial thrombosis in atherosclerotic heart disease patients.

Area of Science:

  • Cardiology
  • Pharmacology
  • Thrombosis Research

Background:

  • Coronary thrombosis is critical in atherosclerotic heart disease development and complications.
  • Pharmacologic strategies targeting hemostasis are central to managing coronary artery disease.
  • Platelets are key cellular components in arterial thrombosis, making antiplatelet therapies highly effective.

Purpose of the Study:

  • To review the role of clopidogrel in treating patients with coronary artery disease.
  • To highlight clopidogrel's mechanism as an antiplatelet agent within the thienopyridine class.

Main Methods:

  • Literature review focusing on antiplatelet therapies.
  • Analysis of clopidogrel's efficacy and mechanism in coronary artery disease.

Main Results:

  • Clopidogrel, a thienopyridine, demonstrates significant efficacy as an antiplatelet agent.
  • Effective management of arterial thrombosis is achieved through platelet inhibition.

Conclusions:

  • Antiplatelet therapy, specifically clopidogrel, is a cornerstone in managing coronary artery disease.
  • Understanding platelet function is crucial for developing effective treatments for atherosclerotic heart disease.

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