Related Experiment Videos
Synthesis, hypoglycemic and toxicological evaluation of new 1,2-benzisothiazolyl derivatives
P Vicini1, L Amoretti, A Caretta
1Istituto di Chimica Farmaceutica e Tossicologica, Università di Parma.
Farmaco (Societa Chimica Italiana : 1989)
|March 1, 1992
Abstract:
The synthesis of 1,2-benzisothiazol-3-ylguanidines, 1,2-benzisothiazol-3-ylbenzensulphonylureas and 1,2-benzisothiazol-3-ylbenzensulphonamides is described. Some of the new compounds showed moderate hypoglycemic activity but most of them caused serious acute toxic effects.