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[Topical corticosteroids].

B Lebrun-Vignes1, O Chosidow

  • 1Service de Pharmacologie, Centre de Pharmacovigilance, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris. benedicte.lebrun-vignes@psl.ap-hop-paris.fr

Annales De Dermatologie Et De Venereologie
|March 26, 2004
PubMed
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Topical corticosteroids revolutionized dermatology, offering diverse strengths for various inflammatory and tumoral skin conditions. Proper selection and application ensure optimal benefit-risk ratios for patients.

Area of Science:

  • Dermatology
  • Pharmacology

Context:

  • Topical corticosteroids have evolved significantly since the introduction of hydrocortisone.
  • Over twenty different corticosteroid molecules, varying in strength, are now available by prescription in France.

Purpose:

  • To review the evolution and current landscape of topical corticosteroid therapeutics in dermatology.
  • To emphasize the importance of selecting the appropriate topical corticosteroid and application method based on clinical context and guidelines.

Summary:

  • The development of topical corticosteroids has transformed dermatological treatment since the 1950s.
  • These agents are effective for numerous inflammatory and tumoral skin diseases.
  • Choosing the right corticosteroid (strength, vehicle) and application method is crucial for maximizing efficacy and minimizing risks.

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Impact:

  • Improved management of inflammatory and tumoral skin diseases through targeted corticosteroid therapy.
  • Establishment of best practices for topical corticosteroid use, ensuring favorable benefit-risk profiles.
  • Enhanced therapeutic options for dermatologists and improved patient outcomes in skin condition management.