Experimental models of human cancer

A dependency map enhanced with next-generation 3D cancer models.

Nature·2026

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer.

Oncotarget·2026

SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.

Nature communications·2026

Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network.

Molecular cell·2026

A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.

Science (New York, N.Y.)·2025

SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.

Research square·2025

The effect of energy metabolism on embryonic development and endometrial receptivity in patients with repeated implantation failure.

Cell cycle (Georgetown, Tex.)·2026

Integrated multi-level transcriptomic and bioinformatics analysis identifies lipid metabolism-ubiquitination signatures and reveals ATG5, ASB4, LDLR, and CD36 as Candidate biomarkers in insulin resistance.

Cell cycle (Georgetown, Tex.)·2026

The role of IL-37 in inflammatory bowel disease and colitis-associated colorectal cancer.

Cell cycle (Georgetown, Tex.)·2026

Exploratory multi-omics links CCL2/TIMP1 axis to immunosuppressive TME in glioblastoma.

Cell cycle (Georgetown, Tex.)·2026

Circular RNA circ_0001829 attenuates G2/M arrest to promote hepatocyte proliferation by sponging miR-3095-3p following liver injury.

Cell cycle (Georgetown, Tex.)·2026

Identification of PGF+ endothelial cells associated with plaque instability in carotid atherosclerosis by scRNA-seq and RNA-seq analysis.

Cell cycle (Georgetown, Tex.)·2026

Decades of intensive care medicine trials: what randomised evidence has changed, corrected, and still questions to resolve.

Intensive care medicine·2026

Pilot Study of Oral Microbiome and Psychoneurological Symptom Cluster in Breast Cancer.

Nursing research·2026

Dietary Terpenoids in Advancing Biofilm-Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano-Facilitated Functional Delivery.

Cell biochemistry and function·2026

Primary small-cell neuroendocrine carcinoma of the bladder: a very rare histological subtype.

Oxford medical case reports·2026

The role of non-coding RNAs in regulating R-loop dynamics in cancer: Mechanisms and therapeutic implications.

Acta pharmaceutica Sinica. B·2026

Iron homeostasis and macrophage polarization in oral squamous cell carcinoma: mechanisms and therapeutic perspectives.

Frontiers in immunology·2026

Related Experiment Videos

Experimental models of human cancer

Related Concept Videos

A dependency map enhanced with next-generation 3D cancer models.

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer.

SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.

Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network.

A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.

SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.

The effect of energy metabolism on embryonic development and endometrial receptivity in patients with repeated implantation failure.

Integrated multi-level transcriptomic and bioinformatics analysis identifies lipid metabolism-ubiquitination signatures and reveals ATG5, ASB4, LDLR, and CD36 as Candidate biomarkers in insulin resistance.

The role of IL-37 in inflammatory bowel disease and colitis-associated colorectal cancer.

Exploratory multi-omics links CCL2/TIMP1 axis to immunosuppressive TME in glioblastoma.

Circular RNA circ_0001829 attenuates G2/M arrest to promote hepatocyte proliferation by sponging miR-3095-3p following liver injury.

Identification of PGF+ endothelial cells associated with plaque instability in carotid atherosclerosis by scRNA-seq and RNA-seq analysis.

Decades of intensive care medicine trials: what randomised evidence has changed, corrected, and still questions to resolve.

Pilot Study of Oral Microbiome and Psychoneurological Symptom Cluster in Breast Cancer.

Dietary Terpenoids in Advancing Biofilm-Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano-Facilitated Functional Delivery.

Primary small-cell neuroendocrine carcinoma of the bladder: a very rare histological subtype.

The role of non-coding RNAs in regulating R-loop dynamics in cancer: Mechanisms and therapeutic implications.

Iron homeostasis and macrophage polarization in oral squamous cell carcinoma: mechanisms and therapeutic perspectives.

Related Experiment Videos

Experimental models of human cancer

Related Concept Videos

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