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Bilateral, uncemented total hip arthroplasty in osteopetrosis
D P Gwynne Jones1, B F Hodgson, N A Hung
1Department of Orthopaedic Surgery, Dunedin Hospital, Dunedin, New Zealand.
The Journal of Bone and Joint Surgery. British Volume
|March 30, 2004
Summary
Bilateral hip replacements using uncemented prostheses were successful in a patient with autosomal dominant osteopetrosis. This approach, despite surgical challenges, offers excellent intermediate-term outcomes for this rare bone disorder.
Area of Science:
- Orthopedic Surgery
- Genetics
- Bone Metabolism
Background:
- Autosomal dominant osteopetrosis (ADO) is a rare genetic disorder characterized by impaired osteoclast function, leading to increased bone density.
- Patients with ADO often develop skeletal complications, including hip abnormalities like degenerative changes and protrusio acetabuli, necessitating surgical intervention.
Observation:
- A 45-year-old woman with ADO underwent bilateral uncemented hip replacements due to degenerative changes and protrusio acetabuli.
- Surgical preparation of the femoral canal presented significant technical challenges during the procedure.
Findings:
- At a ten-year follow-up, the patient exhibited excellent clinical outcomes and radiological results.
- No evidence of osteolysis (bone loss around the implant) was observed, indicating long-term implant stability.
Implications:
- Uncemented hip replacement is a viable and successful intermediate-term treatment option for patients with autosomal dominant osteopetrosis.
- Despite the technical demands, this surgical technique can provide durable results in managing hip complications associated with ADO.