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Updated: Aug 25, 2026

Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound
Published on: May 8, 2012
Compound high-energy limb fractures with delayed union: our experience with adjuvant ultrasound stimulation (exogen)
Alexander Lerner1, Haim Stein, Michael Soudry
1Department of Orthopaedic Surgery A, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, P.O. Box 9602, Haifa 31096, Israel. alex_lerner@yahoo.com
Abstract:
The use of low intensity pulsed ultrasound accelerates cortical and cancellous bone fracture healing. Seventeen patients with eighteen high-energy fractures of the long bones were treated with low intensity pulsed ultrasound supplementation to surgical skeletal stabilization and tissue flaps. Sixteen fractures were healed within 13-52 weeks after starting ultrasound supplementation despite severe soft-tissue injuries and varying degrees of tissue loss. This method may be useful in the combined treatment of high-energy limb injuries.
