Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Spontaneous bacterial peritonitis].

Edna Strauss1, Wanda Regina Caly

  • 1Hospital de Clínicas da Universidade de São Paulo e Hemocentro-Fundação Pró-Sangue, São Paulo, SP. edna.strauss@hcnet.usp.br

Revista Da Sociedade Brasileira De Medicina Tropical
|March 31, 2004
PubMed
Summary

Spontaneous bacterial peritonitis (SBP) affects 30% of cirrhosis patients with ascites. Early diagnosis and antibiotics improve survival, but bacterial resistance necessitates new prophylactic strategies like probiotics.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

WOMEN'S ACHIEVEMENTS IN THE MEDICAL FIELD.

Arquivos de gastroenterologia·2022
Same author

Brazilian Society of Hepatology and Brazilian Society of Infectious Diseases Guidelines for the Diagnosis and Treatment of Hepatitis B.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases·2020
Same author

CHRONIC HEPATITIS C IS STILL A PROBLEM FOR THE PUBLIC HEALTH CARE SYSTEM IN BRAZIL.

Arquivos de gastroenterologia·2019
Same author

RECOMMENDATIONS OF THE BRAZILIAN SOCIETY OF HEPATOLOGY FOR THE MANAGEMENT OF ACUTE KIDNEY INJURY IN PATIENTS WITH CIRRHOSIS.

Arquivos de gastroenterologia·2018
Same author

VARICEAL BLEEDING: UPDATE OF RECOMMENDATIONS FROM THE BRAZILIAN ASSOCIATION OF HEPATOLOGY.

Arquivos de gastroenterologia·2017
Same author

Clinical Features of Refractory Ascites in Outpatients.

Clinics (Sao Paulo, Brazil)·2017

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Gastroenterology

Context:

  • Spontaneous bacterial peritonitis (SBP) is a serious complication in patients with cirrhosis and ascites, carrying high morbidity and mortality.
  • Pathogenesis involves impaired host defenses, microbial overgrowth, and bacterial translocation in end-stage liver disease.
  • Clinical presentation is variable, underscoring the need for ascitic fluid analysis.

Purpose:

  • To review the epidemiology, pathogenesis, diagnosis, treatment, and prevention of spontaneous bacterial peritonitis.
  • To highlight the impact of early diagnosis and antibiotic therapy on mortality rates.
  • To discuss emerging strategies for SBP prophylaxis, addressing bacterial resistance.

Summary:

  • SBP diagnosis relies on ascitic fluid neutrophil count (>250/mm³) and/or bacterial culture, with Enterobacteriaceae, particularly Escherichia coli, being common pathogens.

Related Experiment Videos

  • Intravenous third-generation cephalosporins demonstrate high efficacy (70-95%), and oral norfloxacin prevents recurrence.
  • Short-term antibiotic prophylaxis is advised post-gastrointestinal bleeding; probiotics show promise but require further research.

    • Impact:

    • Mortality from SBP has significantly decreased due to advancements in diagnosis and treatment.
    • Effective antibiotic regimens and prophylactic strategies are crucial for managing SBP in cirrhosis patients.
    • Ongoing research into novel prophylactic agents like probiotics is essential to combat rising antibiotic resistance.