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Updated: Aug 25, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
A facile electrochemical method for synthesis of new benzofuran derivatives
Davood Nematollahi1, Davood Habibi, Mohammad Rahmati
1Department of Chemistry, Faculty of Science, University of Bu-Ali-Sina, Hamadan 65174, Iran. nemat@basu.ac.ir
Abstract:
Electrooxidation of 3-substituted catechols has been studied in the presence of dimedone in aqueous solution, using cyclic voltammetry and controlled-potential coulometry. The results indicate that the quinones derived from catechols participate in Michael addition reactions with dimedone to form the corresponding benzofuran derivatives (6a-c). We propose a mechanism for the electrode process. The efficient electrochemical synthesis of 6a-c has been performed at carbon rod electrodes in an undivided cell using a constant current.
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