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Updated: Aug 16, 2026

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DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis
Published on: October 6, 2017
Unfaithful DNA polymerase caught in the act
1Institute of Molecular Cancer Research, University of Zürich, August Forel-Strasse 7, CH-8008 Zurich, Switzerland.
Molecular Cell
|April 1, 2004
Abstract:
The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site.
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