Myeloma with predominant phalangeal involvement

A case of plasma cell myeloma involving the middle phalanx of the ring finger is reported. This was a case of a non-secretory myeloma; however, monoclonal immunoglobulins were demonstrated by immunohistochemical studies. Plasma cell myeloma with phalangeal involvement is extremely rare: our literature search disclosed only two well-documented cases. Plasma cell myeloma may occur in the hand, so it should be considered in the pre-biopsy differential diagnosis when bone lesions radiologically consistent with myeloma are encountered.