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Dosing problems in the use of topical ophthalmic drops
A Loewenstein1, O Geyer, A Blanc
1Department of Ophthalmology, Ichilov Hospital, Tel Aviv, Israel.
Abstract:
The effect of two drops of the same drug, one instilled immediately after the other, was compared to the effect of a single drop in 100 healthy volunteers. The drugs investigated were tropicamide, 0.125%, and phenylephrine, 2.5%. The mydriatic effect of two drops was 30%-35% stronger than the effect achieved by a single drop.