Related Experiment Videos
Septal polydipsia in rats is a primary polydipsia not mediated by dopamine
1Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.
Indian Journal of Physiology and Pharmacology
|April 1, 1992
Abstract:
Bilateral lesions of nucleus septal lateralis resulted in a sustained and significant increase in water intake, without any change in food intake. Intracerebral injection of dopamine (DA) or of spiperone (a central D2-receptor antagonist) did not elicit any change in water or food intake. The polydipsia resulting from septal lesions is thus a primary polydipsia, which is independent of food intake, and is not mediated by neurotransmitter dopamine.