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Updated: Aug 25, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Subarachnoid hemorrhage
1Department of Neurology, Mayo Clinic School of Medicine and Neurological Neurosurgical Intensive Care Unit, Saint Mary's Hospital, Rochester, MN 55905, USA. manno.edward@mayo.edu
Abstract:
The medical and surgical management of aneurysmal SAH has changed dramatically in the past few decades. Surgical management emphasizes early triage and repair of the responsible aneurysm. Medical management focuses on maintenance of adequate volume, monitoring cerebral vasospasm, and initiation of medical maneuvers or interventional procedures designed to improve vessel patency and CBF. The results of these techniques have not been studied in randomized controlled trials; however, several large retrospective analyses reveal a significant decrease in mortality and morbidity with the institution of these measures. Future improvements will continue to develop with increased understanding of cerebral vasospasm and in neurologic monitoring.
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