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[Ovarian function after oral contraception in infertile patients]
Akusherstvo I Ginekologiia
|April 8, 2004
Summary
This study on infertile patients found that Regulon, a lower-dose ethinylestradiol oral contraceptive, significantly increased ovulation rates compared to Anteovin over two months, aiding ovarian activity recovery.
Area of Science:
- Reproductive Endocrinology
- Pharmacology
Context:
- Investigated ovarian activity in 54 infertile patients.
- Patients received oral contraceptives for two months: Anteovin (0.05 mg ethinylestradiol) or Regulon (0.03 mg ethinylestradiol).
Purpose:
- To assess the impact of two different oral contraceptives on ovarian activity in infertile women.
- To compare the efficacy of Anteovin and Regulon in stimulating follicular development and ovulation post-contraception.
Summary:
- Follicular development and ovulation were monitored using vaginal ultrasonography and serum progesterone levels.
- After one month, ovulation rates were 48.48% (Anteovin) and 71.42% (Regulon).
- After two months, ovulation rates increased to 71.48% (Anteovin) and 85.71% (Regulon), with significant increases in follicular diameter.
Impact:
- Regulon demonstrated a higher ovulation rate compared to Anteovin, suggesting a more effective recovery of ovarian function.
- Findings provide insights into oral contraceptive choices for managing infertility and restoring ovarian activity.