Jove
Visualize
Contact Us

Related Experiment Videos

Hypothyroid acute renal failure.

Sonali Birewar1, Mark Oppenheimer, Edward T Zawada

  • 1Internal Medicine Residency Program, USD School of Medicine, Sioux Falls, SD, USA.

South Dakota Journal of Medicine
|April 8, 2004
PubMed
Summary

Severe hypothyroidism can cause acute renal failure and muscle breakdown (rhabdomyolysis). Prompt thyroid hormone replacement therapy can reverse these serious complications, highlighting hypothyroidism as a critical consideration in patients with unexplained renal and muscle issues.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anxiety-like behavior during protracted morphine withdrawal is driven by gut microbial dysbiosis and attenuated with probiotic treatment.

Gut microbes·2025
Same author

Anxiety-like behavior during protracted morphine withdrawal is driven by gut microbial dysbiosis and attenuated with probiotic treatment.

bioRxiv : the preprint server for biology·2025
Same author

Sleep Delta power, age, and sex effects in treatment-resistant depression.

Journal of psychiatric research·2024
Same author

2023 Canadian Surgery Forum: Sept. 20-23, 2023.

Canadian journal of surgery. Journal canadien de chirurgie·2024
Same author

The relationship between the HDRS insomnia items and polysomnographic (PSG) measures in individuals with treatment-resistant depression.

Journal of psychiatric research·2022
Same author

Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice.

The American journal of psychiatry·2020
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Endocrinology
  • Nephrology
  • Musculoskeletal Medicine

Background:

  • Hypothyroidism is frequently associated with muscular disorders, including hypothyroid myopathy and elevated muscle enzymes.
  • Acute renal failure (ARF) can present with diverse etiologies, necessitating a broad differential diagnosis.

Observation:

  • A 35-year-old male presented with myalgia and acute renal failure, characterized by a serum creatinine level of 2.4 mg/dl.
  • Further investigation revealed severe hypothyroidism, with a thyroid-stimulating hormone (TSH) level exceeding 500 uIU/ml, as the underlying cause of his symptoms.

Findings:

  • Thyroid replacement therapy led to the stabilization and subsequent improvement of both the patient's myalgia and serum creatinine levels.
  • This case underscores that hypothyroidism, though uncommon, is a recognized cause of rhabdomyolysis.

Implications:

  • Hypothyroidism should be considered in the differential diagnosis of patients presenting with acute renal failure, particularly when accompanied by elevated muscle enzymes.
  • Early recognition and treatment of hypothyroidism can prevent or reverse severe complications like rhabdomyolysis and acute kidney injury.

Related Experiment Videos