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Related Experiment Videos

Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment.

Rowena McBeath1, Dana M Pirone, Celeste M Nelson

  • 1The Cellular and Molecular Medicine Program, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Developmental Cell
|April 8, 2004
PubMed
Summary
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Cell shape dictates human mesenchymal stem cell fate. Spread cells become bone cells (osteogenesis), while round cells become fat cells (adipogenesis), controlled by RhoA signaling and cell tension.

Failed At:

2026-07-10T15:01:04.660098+00:00

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