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Enhancing specificity without sacrificing sensitivity: potential benefits of using microvolt T-wave alternans testing
1Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge 02142, USA. rjcohen@mit.edu
Abstract:
The MADIT-II study (Moss et al., N Engl J Med 2002;346:877-883) demonstrated that implantation of a cardioverter/defibrillator (ICD) reduced mortality from 19.8% to 14.2% during 20 months of follow-up in patients with prior myocardial infarction and left ventricular ejection fraction
