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Update: influenza activity--United States, 2003-04 season

    MMWR. Morbidity and Mortality Weekly Report
    |April 9, 2004
    PubMed

    Insights

    This report details US influenza activity from late 2003 to early 2004, noting a peak in late November-December. Influenza A (H3N2) was most common, with most strains similar to A/Fujian/411/2002.

    Area of Science:

    • Epidemiology
    • Virology

    Background:

    • Summarizes US influenza surveillance data from September 29, 2003, to March 27, 2004.
    • Includes information on human infections with avian influenza viruses linked to North American poultry outbreaks.

    Purpose of the Study:

    • To provide a comprehensive overview of national influenza activity during the specified period.
    • To update previous influenza surveillance summaries.
    • To report on concurrent avian influenza virus infections.

    Main Methods:

    • Utilized preliminary data from the Centers for Disease Control and Prevention (CDC) influenza surveillance systems.
    • Analyzed virus isolation data to identify prevalent strains.

    Main Results:

    • National influenza activity reached its peak in late November and December.
    • The predominant virus identified was influenza A (H3N2).
    • Approximately 87% of isolated influenza A (H3N2) viruses showed similarity to the drift variant A/Fujian/411/2002.

    Conclusions:

    • Influenza A (H3N2) was the primary driver of influenza activity during the 2003-2004 season.
    • The genetic similarity of circulating strains to A/Fujian/411/2002 suggests potential antigenic drift.
    • The co-occurrence of avian influenza virus infections highlights the importance of ongoing surveillance.

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