Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Association between Agent Orange and prostate cancer: a pilot case-control study.

Veda Nargund Giri1, Andrea E Cassidy, Jennifer Beebe-Dimmer

  • 1Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, Ann Arbor, Michigan 48109-0946, USA.

Urology
|April 10, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 2025 small island developing states report of the Lancet Countdown on health and climate change: building resilience in the face of rising heat.

The Lancet. Global health·2026
Same author

Minimizing decompression and warming during deep seawater collection increases abundance and activity of autochthonous bacteria and archaea.

The ISME journal·2026
Same author

Prostate Cancer, Genetic Susceptibility, and Risk of Chronic Non-Urological Complications.

The Prostate·2026
Same author

Specialty differences in treatment recommendations for low-risk prostate cancer.

Urologic oncology·2026
Same author

Associations of fine particulate matter pollution components with overall, prostate cancer, and cardiovascular disease mortality in men with prostate cancer: A cohort study.

Environmental research·2026
Same author

Genomic and Transcriptomic Landscapes of MEN1-Wild-Type Low-Grade Metastatic Pancreatic NETs Uncover Key Oncogenic Drivers and Targetable Pathways.

bioRxiv : the preprint server for biology·2026

This pilot study suggests a potential link between Agent Orange exposure and an increased risk of prostate cancer in military veterans. Further research is needed to confirm this association.

Area of Science:

  • Environmental epidemiology
  • Oncology
  • Veterans' health

Background:

  • Prostate cancer is a leading cause of cancer deaths in American men.
  • Previous studies have suggested a possible association between Agent Orange exposure and prostate cancer.
  • Agent Orange is a herbicide used during the Vietnam War.

Purpose of the Study:

  • To investigate the risk of prostate cancer diagnosis in military veterans exposed to Agent Orange.
  • To conduct a pilot study to estimate this association.
  • To explore the clinical features of prostate cancer in relation to Agent Orange exposure.

Main Methods:

  • A case-control study design was employed.
  • Cases of pathologically diagnosed prostate cancer were identified and age-matched with controls (1:3 ratio).

Related Experiment Videos

  • Agent Orange exposure was determined by reviewing computerized medical records.

    • Main Results:

    • The study included 47 prostate cancer cases and 142 controls.
    • Men with prostate cancer were approximately twice as likely to report Agent Orange exposure (OR 2.06).
    • This finding was adjusted for age and race.

    Conclusions:

    • This pilot study indicates a potential association between Agent Orange exposure and an elevated risk of prostate cancer.
    • Larger population studies are required to validate and precisely quantify this association.
    • The findings highlight the importance of continued research into the long-term health effects of Agent Orange exposure.