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Updated: Aug 14, 2026
![Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58641.jpg&w=3840&q=50)
Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
Proposed addendum to previously published fetal dose estimate tables for 18F-FDG
1Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee, USA. michael.g.stabin@vanderbilt.edu
Abstract:
Placental transfer and fetal dose estimates have been published for women in early pregnancy and at the end of each trimester for a large number of radiopharmaceuticals. For the case of (18)F-FDG, a dose was given with no information about placental transfer of the radiopharmaceutical. Recent publications have reported quantitative values for maternal and fetal uptake of (18)F-FDG in primates and new values for (18)F-FDG kinetics. In this article, these data are applied to give radiation dose estimates for the fetus at all stages of pregnancy for (18)F-FDG. The recommended values are 2.2 x 10(-2) mGy/MBq in early pregnancy, 2.2 x 10(-2) mGy/MBq at 3-mo gestation, 1.7 x 10(-2) mGy/MBq at 6-mo gestation, and 1.7 x 10(-2) mGy/MBq at 9-mo gestation.
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