[Pathogenesis of anemia in abdominal typhus]

Morphological parameters of the red cells were studied in 121 patients with typhoid-paratyphoid conditions. To obtain objective clinical data the authors studied the effect of LPS S. anatum on the intact red cells of healthy persons. The correlation of morphological disorders in the red cells of the patients and the controls revealed a significant role of intoxication in their origin. The research conducted revealed a relationship between the disorders in the erythrocyte membranes and the development of anemia in the patients.