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[Effect of ketamine on cerebral circulation of intact and ischemic animals]
V S Melkumian1, N A Khaĭlov, M D Gaevyĭ
1Pharmacology Department, State Pharmaceutical Academy, ul. Kalinina 11, Pyatigorsk, 357500 Russia.
Eksperimental'Naia I Klinicheskaia Farmakologiia
|April 15, 2004
Abstract:
The influence of ketamine on the local cerebral circulation was studied in intact rats and under the conditions of global brain ischemia. The drug increased the local blood flow in intact rats. Despite pronounced hypotension accompanying the global brain ischemia, ketamine helped maintenance of the cerebral circulation.
