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CD4+ and CD8+ T-lymphocyte subsets in Zambian children
Zaza Ndhlovu1, Judith J Ryon, Diane E Griffin
1Virology Laboratory, University Teaching Hospital, Lusaka, Zambia.
Journal of Tropical Pediatrics
|April 20, 2004
Abstract:
Age-related changes in lymphocyte subsets in HIV-uninfected Zambian children are described. The total lymphocyte count and numbers of CD4+ and CD8+ T-lymphocytes declined with increasing age, while the percentage of CD4+ and CD8+ T-lymphocytes changed little during childhood. Girls between the ages of 12 and 71 months had a higher percentage of CD4+ T-lymphocytes and a higher CD4:CD8 ratio than did boys of a similar age.