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Updated: Aug 24, 2026
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Published on: April 12, 2024
Supratentorial malignant ependymoma in childhood: 16 years without relapse after hemispherectomy
R Ahmadi1, H P Schmitt, S Kunze
1Department of Neurosurgery, University of Heidelberg, INF 400, 69120, Heidelberg, Germany. rezvan.ahmadi@med.uni-heidelberg.de
Introduction:
Malignant intracranial ependymomas in childhood have a poor prognosis, supratentorial ependymomas have the poorest clinical course with a survival rate after 5 years of 45%. The most important prognostic factor in these cases is a radical operation, which cannot usually, however, prevent relapse.
Case Report:
We demonstrate the case of a large malignant ependymoma of the left cerebral hemisphere in a child who has so far lived for 16 years without relapse after an extensive but uncomplicated left-sided hemispherectomy. The patient has also shown an improvement in her preoperative neurologic deficits. Her epilepsy, which was difficult to manage preoperatively, has been completely eliminated. She went to a special school for handicapped children and now works there. She does not need any help in handling everyday activities.
Conclusion:
This case shows the significance of complete tumor resection in malignant ependymomas, which may, under certain circumstances, lead to lasting tumor control.
