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Related Experiment Videos

Nonpseudomonal ecthyma gangrenosum.

Hilary L Reich1, Darice Williams Fadeyi, Narayan S Naik

  • 1Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Journal of the American Academy of Dermatology
|April 21, 2004
PubMed
Summary
This summary is machine-generated.

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Ecthyma gangrenosum, typically linked to Pseudomonas sepsis, rarely stems from other pathogens. This case highlights Citrobacter freundii as a cause in an immunocompromised child with leukemia.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Pediatric Oncology

Background:

  • Ecthyma gangrenosum is a severe skin infection.
  • It is most frequently associated with Pseudomonas aeruginosa sepsis.
  • Immunocompromised patients are particularly susceptible.

Observation:

  • An 8-month-old girl with acute myelocytic leukemia presented with perineal ecthyma gangrenosum.
  • The causative agent was identified as Citrobacter freundii, a gram-negative bacterium.
  • Citrobacter freundii is an uncommon cause of cutaneous disease.

Findings:

  • This case expands the spectrum of pathogens associated with ecthyma gangrenosum.
  • Literature review confirms rare associations of non-pseudomonal pathogens.
  • Citrobacter freundii represents a rare, yet significant, etiology.

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Implications:

  • Clinicians should consider a broader range of pathogens in immunocompromised patients with ecthyma gangrenosum.
  • Early identification and appropriate antimicrobial therapy are crucial.
  • Understanding diverse etiologies aids in managing this severe cutaneous manifestation.