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Updated: Aug 24, 2026

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
Published on: January 2, 2015
[Cortico-basal degeneration: the rare form of tau protein disease]
Sławomir Budrewicz1, Magdalena Koszewicz, Małgorzata Góral
1Dział Radiologii Dolnoślaskiego Szpitala Specjalistycznego im. T. Marciniaka-Centrum Medycyny Ratunkowej.
Abstract:
Cortico-basal degeneration is a rare degenerative disease connected with Tau protein pathology. Epidemiology of cortico-basal degeneration is unknown. The authors present a case of 59 years old woman with suspicion of cortico-basal degeneration. The extrapyramidal symptoms mainly on the right side with "alien limb phenomenon" and dystonia of lower limb is observed in our patient. Cortico-subcortical brain atrophy was present in MRI scans. EEG was asymmetrical. No improvement was noticed after L-Dopa. Treatment of amantidine caused the transient improvement.
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