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Extraocular sebaceous carcinoma in a patient with Muir-Torre syndrome
Cynthia R Harrington1, Barbara M Egbert, Susan M Swetter
1Department of Dermatology, Stanford University Medical Center, Stanford, California 94305, USA.
Background:
Sebaceous carcinoma is a rare, aggressive neoplasm that arises from the adnexal epithelium of sebaceous glands and is commonly associated with Muir-Torre syndrome.
Objective:
The metastatic potential of extraocular sebaceous carcinoma warrants a thorough evaluation to establish the extent of disease.
Methods:
We describe a 55-year-old man who presented with an asymptomatic abdominal wall mass 3 years after definitive diagnosis of Muir-Torre syndrome.
Results:
A biopsy of the surgical specimen revealed sebaceous carcinoma.
Conclusion:
Dermatologists are crucial to the early recognition and diagnosis of extraocular sebaceous carcinoma. In our patient with documented Muir-Torre syndrome, continued surveillance allowed for prompt recognition and treatment of this associated cutaneous malignancy.
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