Related Experiment Video
Updated: Aug 24, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Malignant neoplasms of the nose and sinuses]
1Katedra i Klinika Otolaryngologii CM UJ w Krakowie.
Abstract:
The basic condition for starting the oncological treatment of the tumors of the nose and the sinuses is determining whether or not the disease is malignant. However, the operator should remember that occasionally the diagnosis errors may occur. The histopathologic examination performed during the operation may prove useful for that purpose. The tumors should be first operated on and the radiation therapy has to follow the surgery. Tanks to this procedure the 5-year survival rare is 40%. The operational treatment is performed through two approaches; sublabial approach (of two kinds) and lateral rhinotomy which also has several variations. There is no simple, unified division of the kinds of surgical procedures and that is why the operator should always present the description of the operation. The metastases to the lymph noses of the neck necessitate their removal and substantially reduce 5-year survival rate. The tumors which destroy the bone and infiltrate the frontal or/and middle cranial fossa require the additional approach through the cranial fossa and the excision of the dura and/or the brain is necessary. Subsequently the reconstruction of the bone and the dura in layers has to be performed. Any other procedure may cause complications, especially liquorrhoea, after the radiation therapy is finished. There are circumstances allowing to expect the progress in treatment of these tumors in the next five years (the development of the reconstructional surgery) and fifteen years (interference in the genetic structure of the tumor).
Related Concept Videos
Nose and Nasal Cavity
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Cryptococcal Meningitis
Abnormal Proliferation