Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microtechnologies and nanotechnologies for single-cell analysis.

Helene Andersson1, Albert van den Berg

  • 1MESA+ Institute, University of Twente BIOS, the Lab-on-a-Chip Group, PO Box 217, 7500 AE Enschede, The Netherlands.

Current Opinion in Biotechnology
|April 23, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accurate Sizing of Monodisperse Microbubble Suspensions by Optical Attenuation Spectroscopy.

Ultrasound in medicine & biology·2025
Same author

Cytokine-induced memory-like responses in endothelial cells link chronic inflammation to vascular disease risk.

Molecular omics·2025
Same author

Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19.

Lab on a chip·2025
Same author

FORCETRACKER: A versatile tool for standardized assessment of tissue contractile properties in 3D Heart-on-Chip platforms.

PloS one·2025
Same author

Alternative nano-lithographic tools for shell-isolated nanoparticle enhanced Raman spectroscopy substrates.

Nanoscale·2024
Same author

Tracking the dynamics of thrombus formation in a blood vessel-on-chip with visible-light optical coherence tomography.

Biomedical optics express·2023
Same journal

Microbial C1 assimilation pathways for chemical synthesis: from native metabolism to synthetic design.

Current opinion in biotechnology·2026
Same journal

Medicinal plants fermentation: current knowledge and perspectives.

Current opinion in biotechnology·2026
Same journal

Fermented foods: lessons learned from metagenomics.

Current opinion in biotechnology·2026
Same journal

Microfluidic platforms for the transient transfection of mammalian cells: recent developments and challenges.

Current opinion in biotechnology·2026
Same journal

Harvesting insights from recent advances in yeast genomics for predictable and precision wine fermentation.

Current opinion in biotechnology·2026
Same journal

Minimal enzyme cascades for the aromatic-to-aromatic upgrading of lignin monomers.

Current opinion in biotechnology·2026
See all related articles

Researchers propose a "laboratory-in-a-cell" concept, using single cells as platforms for microchip experimentation. This approach leverages nanotechnology for precise control and analysis of cellular environments, advancing cell-based research.

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Cell Biology

Background:

  • Current efforts focus on mimicking single-cell properties for efficient chip design.
  • Cells represent sophisticated natural nanotechnology at atomic and molecular scales.

Purpose of the Study:

  • To introduce and explore the novel "laboratory-in-a-cell" concept.
  • To leverage micro- and nanotechnological tools for cellular experimentation.

Main Methods:

  • Utilizing micro- and nanotechnological tools for precise control of the cellular biochemical environment.
  • Developing methods for single-cell handling and analysis.

Main Results:

  • The "laboratory-in-a-cell" concept enables precise control over the cellular microenvironment.

Related Experiment Videos

  • The approach allows for detailed analysis of single-cell composition.

    • Conclusions:

    • The laboratory-in-a-cell concept offers a promising alternative to mimicking cell properties.
    • Advancements in single-cell handling and analysis methods are crucial for realizing this concept.