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[Ehlers Danlos type IV syndrome presenting with simultaneous dissection of both internal carotid and both vertebral
K Mondon1, B de Toffol, G Georgesco
1Service de Neurologie, CHRU de Tours, France. karl.mondon@wanadoo.fr
Insights
Cervical artery dissection, a common cause of stroke in young adults, can be linked to connective tissue disorders. Ehlers-Danlos syndrome (EDS) is a key consideration for diagnosing and managing these dissections.
Area of Science:
- Neurology
- Vascular Surgery
- Genetics
Background:
- Cervical artery dissection is a significant cause of ischemic stroke in younger populations.
- Prompt diagnosis and management are crucial for preventing neurological deficits.
Observation:
- A 34-year-old patient presented with simultaneous dissection of both internal carotid and vertebral arteries.
- The patient experienced recurrent right-sided motor deficits and persistent otalgia.
Findings:
- Ehlers-Danlos syndrome type IV was diagnosed as the underlying etiology.
- Connective tissue disorders, particularly vascular Ehlers-Danlos syndrome, should be investigated in cases of cervical artery dissection.
Implications:
- Early identification of Ehlers-Danlos syndrome is vital for appropriate patient management.
- Considering genetic connective tissue diseases can improve diagnostic yield in cervical artery dissection cases.
- This case highlights the importance of a comprehensive etiological workup for cervical artery dissection.
Introduction:
Dissection of cervical arteries is a frequent cause of stroke in young subjects.
Case Report:
We report the case of a 34-year-old patient who experienced simultaneous dissection of both internal carotid arteries and both vertebral arteries leading to repeated motor deficit of the right half-body associated with persistent otalgia. Search for an etiology led to the diagnosis of Ehlers-Danlos syndrome type IV.
Conclusion:
Search for the cause of cervical artery dissection must consider connective tIssue disease, particularly vascular forms of Ehler-Danlos syndrome. Diagnostic, therapeutic as well as prognostic aspects are discussed.
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