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Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
[Interaction of the hormonal and immunologic impairments in men with herpetic keratitis]
Abstract:
Data are described in the paper on the significance of hormonal and immunological impairments and on their interrelation within the pathogenesis of herpetic keratitis in males. An evaluation of contents of testosterone, cortisol, CD8+, CD95+ lymphocytes, interleukin-6 and tumor necrosis factor-alpha (TNF-alpha) as well as definition of interrelations between them has a prognostic value for males with herpetic keratitis. A dropping concentration of testosterone as observed in males with severe herpetic keratitis is indicative of the feasibility to add some hormone-correcting drugs to the combined therapy.
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