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Light traffic: photo-crosslinking a novel transport system
Tracy Palmer1, Frank Sargent, Ben C Berks
1Department of Molecular Microbiology, John Innes Centre, Norwich, UK. tracy.palmer@bbsrc.ac.uk
Trends in Biochemical Sciences
|April 27, 2004
Abstract:
The Tat protein transporter is found in the membranes of many bacteria and in plant chloroplasts. This highly unusual transport machine moves folded and often oligomeric substrate proteins across energy-conserving membranes. A recent paper reports the first use of a photo-crosslinking approach to dissect the early recognition events between the transporter and its substrate.