Reloading the retina by modifying the glial matrix
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Updated: Aug 24, 2026
Müller Glia Cell Activation in a Laser-induced Retinal Degeneration and Regeneration Model in Zebrafish
Published on: October 27, 2017
1School of Biological and Biomedical Sciences, University of Durham, South Road, Durham DH1 3LE, UK. r.a.quinlan@durham.ac.uk
Abstract:
Remarkably, removing the major structural elements from astrocytes and Müller glia in the mouse retina makes successful integration and differentiation of stem cells into the retina more likely, as revealed by Kinouchi et al. These ground-breaking results throw up several new conundrums in understanding the process of stem cell recruitment, differentiation and incorporation into the retina, but they also suggest novel ways to treat retinal degenerative diseases.
