Preload and isometric force variability
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Updated: Aug 24, 2026

Biaxial Mechanical Characterizations of Atrioventricular Heart Valves
Published on: April 9, 2019
S Kim1, L G Carlton, K M Newell
1University of Illinois at Urbana-Champaign, 61801, USA.
Abstract:
Two experiments are reported, which examined the relative contributions of preload (resting force level), change of force, and the time taken to achieve the force in determining isometric force variability. The findings showed that change of force is the strongest determiner of peak force variability but that preload and time to peak force have smaller though systematic effects. A formula that predicts peak force variability is proposed, with preload as an additive effect to the ratio between the change of force level and the square root of time to peak force. These findings confirm that these three impulse variables are significant in predicting force variability and that the impact of rate of force on peak force variability is nonlinear.
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