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10:27
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Intestinal bypass syndrome presenting as erythema nodosum
R P Katugampola1, G K Patel, A M Farrell
1Welsh Institute of Dermatology, University Hospital of Wales, Cardiff, Wales. GSRS@katugampola.freeserve.co.uk
Clinical and Experimental Dermatology
|April 30, 2004
Summary
Intestinal bypass surgery for obesity can lead to serious complications like hyperoxaluria and vitamin deficiencies years later. Surgical reversal may be necessary to manage these severe health issues.
Area of Science:
- Gastroenterology
- Nephrology
- Endocrinology
Background:
- Intestinal bypass surgery was a common bariatric procedure for morbid obesity.
- The surgery typically resulted in significant weight loss, averaging 50 kg.
Observation:
- A 66-year-old woman presented with recurrent erythema nodosum-like lesions 12 years post-intestinal bypass.
- She also exhibited signs of renal failure, fat-soluble vitamin deficiencies (night blindness, osteomalacia, easy bruising), and anemia.
Findings:
- Investigations confirmed hyperoxaluria and deficiencies in fat-soluble vitamins A, D, E, and K.
- The patient experienced only temporary improvement with antibiotic treatment.
Implications:
- This case highlights the potential for long-term, severe complications following intestinal bypass surgery.
- Surgical reversal of the bypass was required to halt the progression of these debilitating health issues.
- Approximately 24-30% of patients with similar complications undergo surgical reversal.
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