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Published on: April 21, 2012
Acute paraplegia associated with vasculitis in a dog with leishmaniasis
A Font1, J Mascort, J Altimira
1Hospital Ars Veterinaria, Carrer Cardedeu 3, 08023 Barcelona, Spain.
Abstract:
A 14-month-old female crossbreed dog with leishmaniasis, receiving allopurinol, was presented with acute paraplegia. A diagnosis of renal failure with pelvic limb lower motor neuron signs was made and the dog was euthanased. Histopathological examination demonstrated leukocytoclastic vasculitis in multiple organs. Malacia and haemorrhage affecting the spinal cord was associated with multiple foci of vasculitis within the nervous tissue. Rupture and thrombosis of inflamed vessels caused haemorrhage in the spinal cord and subsequent paralysis.
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